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70,71 Neuregulin 1 (NRG1), through its receptors ErbB2 and ErbB4, also plays a pivotal role in cardiomyocyte proliferation and heart regeneration in both mouse and zebrafish models by activating key signaling cascades, such as ERK, Akt and GSK-3/-catenin

Additionally, Ozempic and Wegovy are approved to treat heart disease in people with established heart disease who also have type 2 diabetes (Ozempic) or excess weight (Wegovy)

Research from 2021 suggests that dietary changes promoting the bodys natural release of GLP-1 could be useful for managing obesity and type 2 diabetes