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Assessment of aorta endothelial function Endothelium-dependent vasorelaxation was assessed in isolated aortic ring preparations from perfused WT and VECAD IGF- 1R KD animals to evaluate the impact of endothelium-specific IGF- 1 signaling deficiency on vascular function

However, it is well known that mitochondrial and cytosolic GSH levels are decoupled during cell death and many other biological processes 40