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however, it should be emphasised that this model is hypothetical and requires further evaluation before being translated to practice (Figures 1 and 2)
These mechanisms make GLP-1 a key target in managing metabolic health and weight
In clinical trials, tirzepatide demonstrated significant reductions in hemoglobin A1c levels (up to 2.5% reduction in SURPASS diabetes trials) and body weight (up to 20% reduction in SURMOUNT obesity trials) compared to placebo and other medications
It mimics natural hormones that regulate insulin and metabolism
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