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That's a reason to keep on top of your nutrition and strength-training while on these drugs, he writes, "especially for older people like me, who are [already] susceptible to muscle loss." There are people who should steer clear of GLP-1 drugs, Kessler notes, including those with a personal or familial history of certain thyroid and endocrine cancers, those with chronic kidney disease, pancreatitis, inflammatory bowel diseases, uncontrolled diarrhea or constipation or gastroparesis, or if you are pregnant
Despite the successful trial, 10.6% of participants discontinued the 36mg and 12mg treatment due to adverse effects, compared to 4.6% in the placebo group
Those with Severe Kidney Disease: The medication can potentially worsen kidney function in some cases
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