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Applying the cell-based coagulation model in the management of critical bleeding

These contrasting results suggest a concentration-dependent effect of NO and highlight the potential of regulating NOS enzymes as a therapeutic approach

Adinolfi S, Patinen T, Deen AJ, Pitknen S, Hrknen J, Kansanen E, et al

Presence, activity and properties of glutaredoxins are often analysed in coupled spectrophotometric reductive assays with bis(2-hydroxyethyl)disulfide (HEDS) as a non-glutathione substrate 10,11,12,15,16,17,18 or L-cysteine-glutathione disulfide (GSSCys) as a glutathionylated substrate 10,11,12,18,19,20,21 (Fig