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doi: 10.1016/j.yexcr.2017.02.012 93 VillanuevaMT

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Specifically, we found that GSSG elevation suppressed the phosphorylation/activation of IKK-, a proximal kinase in the NF-B signaling pathway that phosphorylates IB-, leading to its proteasomal degradation and subsequent NF-B activation

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Additionally, PKC can lead to insulin resistance and exacerbate insulin dysfunction (80)

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