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While definitive answer to the source of all myofibroblasts that are associated with the lens following its injury will likely await genetic lineage tracing approaches, much is known about the cell signaling pathways required for myofibroblast production and prolonged maintenance following injury/surgery, all of which are potential entry points for the development of drug based therapeutic interventions capable of reducing PCO incidence following cataract surgery (185, 214217)
We can more easily show the impact of using a patent thicket strategy, where a drug manufacturer abuses the patent system through excessive and overlapping patents to increase the exclusivity period for their drug
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