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Together with IL-3, IGF-I stimulates differentiation and proliferation of myeloid cells and has been shown to regulate lymphopoiesis by stimulating proliferation and differentiation of T and B cells in lymphoid organs (Heemskerk et al.)
In individuals with obesity, at a daily dose of 50 mg, it achieved a 17.4% reduction in body weight over 68 weeks of treatment in the OASIS 1 trial37 (Table 1), attributed to its appetite-suppressing and satiety-enhancing effects
Aim to drink at least eight 8-ounce glasses of water daily
Avoid: Sugar-sweetened beverages (soda, sweet tea, energy drinks) Candy and sweets White bread, white rice, and refined pasta Sugary cereals Cookies, cakes, and pastries Processed snack foods Alcohol Alcohol can significantly worsen nausea and gastroesophageal reflux while on GLP-1 therapy
