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The pivotal trial supporting its 2010 FDA approval enrolled 816 HIV-infected adults with clinically defined lipodystrophy, and Phase 3 data documented visceral fat reductions of roughly 15-18% over 26 weeks of treatment a result robust enough to clear FDA review for a defined medical indication

Because B12 is so integrated into our biological processes, a deficiency can manifest in various ways, some of which are subtle and easily overlooked

Research indicates that inadequate thiamine can lead to fatigue, irritability, and impaired cognitive function

At the same time, a vitamin B12 deficiency is only one possible contributor toward an iron deficiency