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Description

IGF-1 LR3 also has reduced binding affinity for IGF-binding proteins (IGFBPs), which normally sequester IGF-1 in circulation and limit its bioavailability

Split dosing typically follows a 60/40 or 50/50 distribution

Spaniol are the supervising physicians.

UK-based trials can be found via the NIHR's Be Part of Research platform (bepartofresearch.nihr.ac.uk), the ISRCTN registry (isrctn.com), and ClinicalTrials.gov for multinational studies