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The no-observed-adverse-effect level (NOAEL) was set at 50mg/kg, the highest dose tested
The Kraus 2014 Nature Paper: Why Adipose Research Specifically The 2014 Nature paper by Kraus and colleagues (titled "Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity") established the adipose-NNMT connection that anchors all subsequent NNMT-inhibition research in fat biology
Keep vials away from direct light (use amber vials or wrap in foil if needed) Never store near heat sources or leave at room temperature for extended periods Label each vial with the reconstitution date Do not use solutions that appear cloudy, discolored, or particulate (beyond expected slight opacity) BAC Water Mixing Reference The volume of bacteriostatic water you add directly determines the concentration of your solution and therefore how many syringe units equal your target dose
[PMID: 28516373] PubMed record related to this compound for laboratory literature review
