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Several peptides with strong physiological phenotypes were identified before their receptors were cloned or fully characterized, limiting structureactivity relationship studies and medicinal chemistry optimization
10.1371/journal.pone.0187964 91 Costas-FerreiraC.DurnR.FaroL
The combination with lemon verbena (as in Metabolaid) appears to be more effective than either ingredient alone, suggesting a synergistic relationship
The compound is stable at pH 5.5-7.0 and should not be mixed with chelating agents (EDTA) that would strip the copper ion
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