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Moroo I, Yamada T, Makino H, Tooyama I, McGeer PL, McGeer EG, et al
The requirement of a protein pre- or post-organ and -animal development is an important distinction that is not always considered in studies involving tissue-specific knockout mouse models but potentially requires additional investigation
, adalimumab, infliximab, certolizumab, canakinumab, tocilizumab, sarilumab, and secukinumab) are monoclonal antibodies and have special targets like tumor necrosis factor (TNF)-, interleukin (IL)-6, IL-1, and IL-17 ( Although the above mentioned DMARDs have been quite successful in mitigating RA, it is still an undeniable fact that a significant proportion of patients could experience treatment failure, including nonresponse and limited efficacy ( With the deepening of research and exploration, many molecules are identified to exert important roles and bring novel insights to prevent RA
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