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Intervention with the DPP-4 inhibitor vildagliptin inhibited the Beclin-1-Bcl-2 interaction and enhanced both LC3-II protein and autophagosomes in the non-infarcted region in OLETF rats without normalization of either AMPK/ULK-1 or mTOR/S6 signaling
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Kidney Issues GLP-1 drugs can sometimes impact kidney function, manifesting as: Dehydration, often due to nausea and vomiting Changes in urination patterns Swelling in the legs or ankles Patients with pre-existing kidney conditions should discuss GLP-1 treatments with their healthcare provider to assess potential risks
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