Uricosuric agents, exemplified by benzbromarone, enhance urinary urate excretion via regulation of renal transporters (e.g., OAT1), although hepatotoxicity limits chronic use (Sun et al., 2025)
14,15 Potential Direct Effects on the Heart Although the systemic indirect effects of GLP-1RAs are well established as the primary drivers of their clinical benefit in HF, emerging preclinical and mechanistic evidence suggests GLP-1RAs may also exert some direct cardioprotective effects, as discussed below
How Stress Affects the Hair Cycle Your hair goes through three main phases: anagen (growth), catagen (transition), and telogen (resting)
Retratrutide has shown even greater percentage weight loss than other medications in this category and may be an option for those few who did not fully respond or have plateaued on their weight loss from other medications