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Indeed, current guidelines do not recommend administration of PDE5i to patients with unstable angina, severe congestive heart failure, or uncontrolled hypertension, patients at high risk for arrhythmias, and patients receiving nitrates [13]
Early announcements highlighted a deal with Pfizer and indicated that companies like AstraZeneca and Merck would participate for certain brand medications
Integration with digital health platforms, structured lifestyle programs, or complementary medications could further enhance outcomes
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