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Besides classical targets, FoxOs also regulate noncanonical E3 ligases such as MUSA1, FBXO31, SMART (FBXO21), and Itch, with FoxO3 as the dominant factor (Li et al., 2022)

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The European Food Safety Authority approved pasteurized Akkermansia as a novel food in 2021 (EFSA Journal, 2021)

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Finally, KPV steps in to manage the immune response, making sure everything proceeds smoothly

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