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doi:10.3389/fphar.2025.1542269
This process involves the action of hydrochloric acid and digestive enzymes in the stomach
Within minutes of starting to eat, however, cells in your gut also rev into action and start secreting two peptide hormones--glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1)
The FDA-approved prescribing information recommends gradual dose titration specifically to minimize gastrointestinal tolerability issues, allowing the digestive system time to adapt to the medication's effects on gut function
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