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doi: 10.1007/s00018-020-03536-5 27 BackertSNeddermannMMaubachGNaumannM
10.3390/pharmaceutics13111945 18 CaoZ.LiuB.YanL.ShuH.WangL.LiL.et al (2024)
On the other hand, in cholestatic individuals in whom the NGS panels have not found pathogenic mutations, a comprehensive study like WES, performed over the full exome, can find potential gene candidates for a cholestasis association, as was the case with the most recently discovered PFIC, PFIC 13 [37, 90]
When combined in the KLOW peptide blend, researchers can examine whether coordinated dosing leads to additive or synergistic effects on endpoints such as histology, gene expression, or functional performance metrics in animal models
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