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Funding This work was partially supported by the National Key Research and Development Program of China (2020YFA0908300), the Jiangsu Provincial Natural Science Foundation (No
4 found that erastin acts on VDACs, leading to mitochondrial dysfunction and resulting in a large amount of released oxides, eventually leading to iron-mediated cell death
It was the first synthetic antimalarial agent and has since gained FDA approval for the treatment of methemoglobinemia
6 Department of Mathematics, Cleveland State University, Cleveland, Ohio, USA
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