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These effects are tied to changes in gut-derived hormones, which may further modulate insulin dynamics, satiety, and energy balance

While GLP-1 medications provide powerful support for weight management, the degree of weight loss depends heavily on adherence to a modest caloric deficit below total daily energy expenditure and on engaging in regular physical activity to increase caloric utilization, he explains

No specific external funding was received for this assistance beyond the funding disclosed for the underlying research project

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