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By integrating high-resolution spatial metabolite profiling with molecular validation, the researchers discovered that TZP disrupts tumor glucose metabolism by inhibiting glycolysis and the tricarboxylic acid (TCA) cycle, leading to energy deprivation in CRC cells and tumor growth suppression
It is recommended to gradually increase the dose (Fras et al., 2019) or take the drug after meals to reduce these adverse reactions
Your healthcare provider should show you how to use semaglutide before you use it for the first time
SURMOUNT did so for tirzepatide (NEJM, 2022)
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