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This article examines the evidence surrounding B12 supplementation, optimal timing for those who require it, and safe, effective use within the context of metabolic health and weight management

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Ultimately, the best care for NDDs might involve combining both: for example, using a disease-modifying drug to reduce protein aggregation in the brain and a microbiome therapy to reduce inflammation and enhance resilience

Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants