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Dosing regimens typically start at 500 mg twice daily, titrated up to 1.53 grams per day [5]
If any adverse effects persist, consult a healthcare provider
Never combine medications without clinical guidance
Typical titration schedule in trials: Start at 2 mg weekly Increase every 4 weeks: 2 mg 4 mg 6 mg 9 mg or 12 mg (depending on target dose) This means it takes 3-4 months to reach the maximum dose Meaningful weight loss becomes apparent after reaching therapeutic doses and maintaining them for several weeks
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