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It results from the oxidation of cellular membrane polyunsaturated fatty acids (PUFAs) by reactive oxygen species (ROS) forming bioactive lipid peroxidation products (Fig
Furthermore, the protection of tea polyphenols is more potent than that of sulfhydryl group-containing compounds, including GSH [26]
Results demonstrated a prolonged circulating half-life consistent with the peptide's albumin-binding design, supporting the once-weekly administration schedule that has remained consistent throughout subsequent development
Most peptides use an alpha-linkage
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