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Indications for use GLP-1 receptor agonists are used to manage type 2 diabetes and, in some cases, for weight loss in people with obesity or who are overweight with related health conditions
These medications work by mimicking a natural hormone that regulates appetite and digestion
Dose adjustment is not recommended in patients with mild-severe renal impairment (eGFR = 15-89 mL/min/1.73 m 2 ), but use is not recommended for patients with end-stage renal disease (127)
The authors explain, Patients had a similar mean percentage weight loss across the BMI subgroups, with those escalated to the 4.5 mg dose having an average weight loss of around 5% in the overall study population and in each BMI subgroup. How well Trulicity works for weight loss on an individual basis will depend on individual factorsranging from your genetics to your health history
