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Para manejar esta situacin, la Agencia Espaola de Medicamentos y Productos Sanitarios (AEMPS) ha emitido unas recomendaciones para los prescriptores (ver nota informativa completa): Priorizar el uso de estos tratamientos de acuerdo con las condiciones autorizadas (control glucmico de pacientes con DM2)

The product's own label includes the standard FDA disclaimer: these statements have not been evaluated by the Food and Drug Administration

However, the gain in bone mass was lost with prolonged treatment of NHC, and the CHC treatment resulted in a significant decrease in long bone BMD, likely due to significant increases in SHBG levels by both OCs

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