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Another thiol-antioxidant, NAC (a precursor of GSH) has also shown great potential to disrupt multispecies endodontic biofilms, suggesting its potential use in root canal and dental plaque treatment ( Mycobacterium tuberculosis ( Funding This work was supported by the University of Sydney Postdoctoral Research Fellowship to TD and by the University of Sydney to TD and JM
Peptides capable of binding copper ions have become an area of research due to their potential role in: Cellular signaling mechanisms Peptidemetal interactions Structural and biochemical modeling Tissue and extracellular matrix research models GHK-Cu is one of the most widely referenced copper peptides in scientific literature, making it a frequent subject of in vitro and ex vivo research
While convenient, these products have limitations: Shorter usable lifespan
A recent review has documented this synergy (McGuire et al., Curr Rev Musculoskelet Med 2025)
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