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[Abstract]2022 Dec;9(34):e2203088

Journal of Herbal Medicine 4 (4)

Therapeutic Advances in Infectious Disease , vol

Figure 13 illustrates the effects of prenatal exposure to VPA, showing that HDAC inhibition may exacerbate oxidative stress by dysregulating the expression of genes involved in the antioxidant response, thereby promoting redox imbalance through increased ROS production and impaired antioxidant defenses (Gottlicher 2001