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Visible pigmentation remains for 48 weeks post-dosing as melanin-containing keratinocytes turn over
De combinatie van deze drie routes levert een synergetisch effect op: de eetlust wordt onderdrukt (GLP-1 + GIP), de insulinegevoeligheid verbetert (GLP-1 + GIP), en het lichaam verbrandt actief meer vet (glucagon) zelfs in rust
The dose is increased gradually every four weeks, up to a maximum of 15mg
However, as seen in Figure 4b, the relationship is somewhat variable and may be driven by a limited number of participants
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