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Mechanism of Action Melanogenesis Stimulation: Activation of MC1R stimulates the synthesis and release of eumelanin (the protective, dark pigment, typically black/brown), as opposed to pheomelanin (the red/yellow pigment)

35 Moreover, the COX pathway has also been implicated in the risk of developing BE, the precursor lesion to EAC

For example, bentonite, a clay mineral consisting of aluminium silicate sheets with a high surface area, was formulated into a nasal spray (AM-301) to protect against SARS-CoV-2 and other airborne pathogens 20

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