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Rev Infect Dis 4(2):426428 Nguyen AT, Gentry CA, Furrh RZ (2013) A comparison of adverse drug reactions between high- and standard-dose trimethoprim-sulfamethoxazole in the ambulatory setting

Binds extracellular and exchangeable copper(II) ions with high affinity, facilitating copper delivery into cells and enhancing the action of copper-dependent enzymes necessary for extracellular matrix synthesis and antioxidant defenses 2