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Direct-to-consumer platforms, such as LillyDirect or NovoCare, make FDA-approved GLP-1s accessible to their population, and employers can support them with behavior change tools to optimize either form of the GLP-1
[10] [11] Small clinical trials of liraglutide in HFrEF (FIGHT and LIVE) have shown heart rate increases and potential safety signals, suggesting caution in this population
Careful dose titration is essential, starting with the lowest available dose (2.5 mg weekly) for initiation only, with increases every 4 weeks as tolerated to reach therapeutic doses per FDA labeling
Titration Adjustment Period When you move to a higher dose, a 23 week stabilization period is completely normal
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