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* Correspondence: Gianna Dipalma [email protected] Francesco Inchingolo [email protected] These authors have contributed equally to this work and share first authorship These authors have contributed equally to this work and share last authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Peptides are short chains of amino acids that are vulnerable to enzymatic breakdown

Effect of drugs that affect P450 activity The toxicity of acetaminophen is due to the action of several P-450 cytochromes (CYPs) that catalyze the synthesis of NAPQI from APAP

Mounjaro and Zepbound contain the same active drug, tirzepatide, in the same titration ladder