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Attenuated but clinically relevant gains in event-free survival were observed in analyses assuming 50% additive effects of combination therapy, including for major adverse cardiovascular events (2.4 years [95% CI, 1.13.5]), chronic kidney disease progression (4.5 years [95% CI, 2.85.9]), and all-cause death (1.8 years [95% CI, 0.72.8])

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