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However, protecting your muscle mass is essential for long-term function and pain prevention

Federal law excludes weight loss drugs from Medicare Part D, which means patients prescribed Wegovy for obesity management usually have to pay out of pocket

Week 1 after stopping: Drug levels begin decreasing Appetite suppression typically remains strong Week 2: Significant reduction in drug concentration Metabolic effects still present Week 3: Drug levels become low Appetite control may begin decreasing Week 45: Most of the medication is cleared Physiological effects gradually fade This slow elimination helps prevent sudden changes in appetite or blood sugar regulation