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Dulaglutide and Semaglutide | Dosage Comparison Dulaglutide and semaglutide are both suitable for once-weekly subcutaneous administration due to their favorable pharmacokinetics and extended half-lives [1, 9]

This dependency can feel discouraging for patients who hoped for a permanent fix. It reinforces the idea that semaglutide should be seen as a tool to aid weight loss efforts, not a replacement for sustainable healthy habits

It means the benefit-risk profile must be proven through adequate trials, regulatory review, and continued safety monitoring

The effect was much stronger among individuals with diagnosed alcohol use disorder or hazardous drinking patterns