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The MTHFR enzyme creates the methylfolate
Acute or short term side effects may include: Stomach or abdominal pain Nausea or stomach upset Indigestion Constipation Headache Dizziness Drowsiness Fatigue Tinnitus Fluid retention Long term side effects may include: Chronic stomach pain, heartburn, or nausea Increased risk of gastrointestinal bleeding Small bowel inflammation (1) Increased risk of stomach ulcers Increased risk of heart disease and cardiovascular events including heart attack, stroke, and heart failure Increased risk of kidney disease or kidney failure Neither of these are complete lists, and some people may be at a higher risk of experiencing serious side effects
The recommended initial dosing of IGlarLixi for patients previously uncontrolled on lixisenatide or on less than 30 IU basal insulin is 15 U (15 U of glargine and 5 mcg of lixisenatide)
& Kujala, U
