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When this happens, GLP-1 medications lose their effectiveness because there are insufficient beta cells to respond to the GLP-1 signal

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To examine differences between semaglutide or tirzepatide and first-generation GLP-1RAs in their associated risk for NAION and other optic nerve and visual pathway disorders, we performed a head-to-head comparison of semaglutide or tirzepatide with other GLP-1RAs and a head-to-head comparison of semaglutide with tirzepatide

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