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While this can benefit overall health, sudden changes in body weight may place stress on the body and disrupt the normal hair growth cycle
Genetic predispositions in peptide signaling pathways (GIPR, MC4R, FTO variants) can support more informed conversations with providers about expected dose ranges and titration pace, though they do not predict exact individual response
In the STEP trials, semaglutide produced average weight loss of 1518% at the 2.4 mg maintenance dose, with approximately 80% of participants achieving clinically significant (5%) weight loss
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