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Allergic or inflammatory reactions Some people report developing a Wegovy skin rash, itchy skin, or hives

Deli MA, Porkolb G, Kincses A, Mszros M, Szecsk A, Kocsis AE, et al

Pharmacokinetics of tirzepatide demonstrated dose proportionality over the wide dose range, with C max of 180 nM in individuals treated with one dose of 8 mg and a C max of 260 nM with 15 mg/week dose in the clinical study, exceeding the EC50 values for GIPR and GLP-1R activations by approximately 10,000-fold and 250-fold, respectively (63)