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In March 2024, the FDA expanded Wegovys approval to include reducing cardiovascular risk in people with obesity and existing cardiovascular diseasea major milestone for these treatments

While traditionally recognized for its role in hydrogen sulfide oxidation within mitochondria, SQOR has now been shown to also utilize hydrogen selenide as an alternative electron donor for the reduction of ubiquinone (CoQ 10 ) to ubiquinol (CoQ 10 H 2 ) 24

[2] Current clinical guidance from the American Diabetes Association acknowledges this uncertainty, recommending that healthcare providers remain vigilant for pancreatitis symptoms but not avoid GLP-1 receptor agonists solely based on theoretical pancreatic concerns

Metformin use associated with protective effects for ocular complications in patients with type 2 diabetes - observational study