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Problem: nausea that does not improve after 2 weeks at a new dose Standard advice says nausea resolves within 1 to 2 weeks of each dose increase
Reductions of this magnitude are rare in addiction medicine and whats remarkable is that the finding came from drugs initially designed for diabetes, later repurposed for obesity and never intended to treat addiction
Other important side effects include gallbladder disease (cholelithiasis, cholecystitis), and potential worsening of diabetic retinopathy (particularly with rapid HbA1c reduction on semaglutide)
When this process slows down, food remains in the digestive tract longer than usual, creating an environment where bacteria, primarily in the small intestine and colon, can ferment sulfur-containing compounds more extensively
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