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However, only poly(I:C) treatment results in elevated IL-8 transcript levels and increased nitric oxide production (41) identified distinct regulatory patterns of TLR expression in chicken erythrocytes: TLR3 expression is significantly upregulated following stimulation with recombinant TNF (rTNF) but is downregulated after treatment with poly(I:C) and peptidoglycan (PGN)

Also, DAG might turn on an enzyme called protein kinase C (PKC), which may add phosphate groups to other signaling molecules

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Furthermore, SIRT3 can deacetylate lysine residues on ALDH2, thereby opening up targets for NAPQI binding and inactivation of the enzyme [88]