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Treatment with only NR in fly models of PD increased NAD + levels, markers of UPR mt , mitophagy, and improved climbing function 278

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But also works by slowing the movement of food through the stomach and may decrease appetite and cause weight loss

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Moreover, OCTN2 mediates the tissue distribution of carnitine, ensuring that these tissues receive sufficient carnitine to maintain their normal functions [164]

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*Number of participants in the full analysis set

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