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"These drugs are thought to work by engaging part of the brain called the hypothalamus, which helps regulate a wide variety of hormones," says Jena Shaw Tronieri, Senior Research Investigator at Penn's Center for Weight and Eating Disorders and a co-author of the study

Gradual dose escalation , as recommended in prescribing guidelines, allows your body to adapt to the medication and may reduce the severity of side effects, including fatigue

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