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Mitochondrial ATP-synthase in the entorhinal cortex is a target of oxidative stress at stages I/II of Alzheimer's disease pathology
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As a result, it breaks down on the way, and you do not get the full benefit
These data are in line with the previous study reported in vitro for macrophages and human smooth muscle cells, in which -tocopherol inhibits uptake of oxLDL by downregulating CD36 expression (Devaraj et al., 2001)
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