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Patients seeking medical weight-loss treatment now may discuss currently available options such as Semaglutide-based or Tirzepatide-based weight-loss treatment with a licensed provider when clinically appropriate

Its multifaceted effects stem from its impact on inflammatory cytokines and mitochondrial function 1

Stop around two months before planning to conceive

Finally, some cosmetics, photosensitizing drugs (e.g., phenothiazines, sulfonamides, sulfonylureas, thiazide diuretics, tetracyclines, tricyclic antidepressants, promethazine, piroxicam), and steroid hormones (e.g., contraceptive pills, estrogen replacement therapies) increase the melanogenic effect of sun exposure and should be substituted to enable successful melasma treatment [24,25,26,27]