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Neuroinflammation Neuroinflammation is a critical pathogenesis of neurodegeneration, and diabetes significantly and systemically enhances inflammation, including that in the brain
606 By activating autophagy and inhibiting ferroptosis, rapamycin reduces the loss of dopamine neurons in the substantia nigra and improves behavioral symptoms in PD model mice, suggesting that the mutual regulation of ferroptosis and autophagy may provide therapeutic targets for drug therapy of PD
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