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In REDEFINE 2, which included participants with type 2 diabetes (a population that typically shows lower weight loss with any intervention), CagriSema achieved 13.7% weight loss compared to 3.4% with placebo
This mechanism has been characterised in multiple pre-clinical studies, with particular focus on tendon and ligament repair outcomes
Participants not only lost weight but also kept it off, with significant improvements in overall health
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